منابع مشابه
The Pathogenesis of Thrombosis
© 2002 Blackwell Science Ltd ‘I call him a perfect physician who judges it better to abstain from treatment than pursue one which might perturb the course of the malady’ (Maimonedes, 1125–1204). This might well apply to long-term anticoagulation, with the inevitable risk of bleeding, in a patient with deep venous thrombosis who is found to have factor V Leiden. There is no evidence that the ris...
متن کاملPathogenesis of carotid thrombosis.
We histologically examined specimens from 11 patients with recent occluding thrombi at the carotid bifurcation to study local factors in the vessel wall that precipitated the thrombi. The area of stenosis of the vessel lumen was determined morphometrically. Severe atherosclerotic stenosis was frequent but was not a prerequisite for thrombus formation since specimens from almost one half of the ...
متن کاملPathogenesis of Serum-induced Venous Thrombosis
The mechanisms involved in the initiation, propagation, and dissemination of intravascular clots remain obscure. The identification of each new clotting factor has raised the possibility that abnormalities in these factors might be found among patients with thromboembolism. Data have yet to be presented, however, demonstrating a causal relationship between intravascular thrombosis and an altera...
متن کاملThrombosis in vasculitis: from pathogenesis to treatment
In recent years, the relationship between inflammation and thrombosis has been deeply investigated and it is now clear that immune and coagulation systems are functionally interconnected. Inflammation-induced thrombosis is by now considered a feature not only of autoimmune rheumatic diseases, but also of systemic vasculitides such as Behçet's syndrome, ANCA-associated vasculitis or giant cells ...
متن کاملRetinal vein thrombosis: pathogenesis and management.
Retinal vein occlusion (RVO) is the most common retinal vascular disease after diabetic retinopathy. Owing to its multifactorial nature, however, management of this condition remains a challenge. Of the two main types of RVO, branch retinal vein occlusion (BRVO) is more prevalent than central retinal vein occlusion (CRVO). Most patients develop the disease at an elderly age, and more than half ...
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ژورنال
عنوان ژورنال: Nature
سال: 1960
ISSN: 0028-0836,1476-4687
DOI: 10.1038/185937a0